About the Symposium

Drug discovery identifies potential new therapeutic entities using computational, experimental, translational, and clinical models. Despite advances in biotechnology and understanding of biological systems, drug discovery is still lengthy, costly, and difficult with a high attrition rate of new therapeutic discovery. A complete drug discovery business process typically involves four phases: Early Drug Discovery, Pre-Clinical Phase, Clinical Phases, and Regulatory Approval.

The First Cannabinoid Translational Science Symposium aims to strengthen connections between all the actors of the drug discovery process in the cannabinoid field. Experts who design the new chemical entities will be brought into contact with experts who validate the therapeutic potential of such molecules at the pre-clinical or clinical levels and specialists in regulatory affairs who deal with organization adherence to regulatory compliance.

To favor productive dialogs between all stakeholders, at the end of each scientific session, all speakers will participate in chaired panel discussions to foster and translate cannabinoid science into practice.

Why a cannabinoid translational science symposium?

Cannabinoids are molecules acting on a tightly regulated and complex system (the endocannabinoid system), which represent a promising therapeutic strategy for a plethora of treatments. Despite the enormous progress and knowledge of devoted research and technological advances to date achieved, the exploitation of the cannabinoid therapeutical potential is not at its maximum yet. Translating a scientific discovery from the laboratory to human application involves a series of challenges. We do believe that fostering communication between the key stakeholders is a mandatory action needed to succeed in such a goal.

The Cannabinoid Translational Science symposium aims at gathering a diverse range of speakers and discussion leaders from different institutions, organizations, and industries worldwide and it is mainly focused on strengthening a bridge between companies and academics working in the cannabinoid field.

Chairs:

Alessia Ligresti and Marialessandra Contino

Scientific committee:

Carmen Abate (UniBA), Angela Stefanachi (UniBa), Giuseppe Mangiatordi (CNR), Fabiana Piscitelli (CNR)

Organizing committee:

Daniela Esposito (CNR), Giovanni Graziano (UniBA)

Editions and Promotions

Registrations are now officially open!

The first edition of the Cannabinoid Translational Science Symposium will be held remotely
on February 2025, Monday 10th, Monday 17th, and Monday 24th.

Each day a different theme will be deepened:

  • Neuroinflammation
  • Oncology and Pain
  • Trials for Therapeutic and Drug Development Purposes

 

WHO SHOULD ATTEND?

 

This is a must-attend symposium for professionals from across the cannabinoid research field.
Academics and Researchers
Scientists and Technologists
Medical Professionals
Regulatory Specialists and Evaluators of Clinical Performance

 

Discover the symposium agenda

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    SYMPOSIUM AGENDA

    10th February 2025

    DAY 1

    TACKLING NEUROINFLAMMATION WITH CANNABINOIDS

    The Symposium will be held virtually from 9:30 – 17:00 CET

    9.20-9.30 – Welcoming (Alessia Ligresti and Marialessandra Contino)
    Chairs: Marialessandra Contino and Maria Laura Bolognesi

    9.30 – Prof. Michael Decker (University of Würzburg)
    Neuroprotective strategies for Alzheimer's disease drug development

    10.00 – Prof. Mauro Maccarrone (University of L’Aquila)
    A biochemical perspective on the interaction between endocannabinoids and other bioactive lipids in neuroinflammation

    10.30 – Dr. Brendan Hughes (European Union Drugs Agency)
    An international regulatory perspective on cannabis and cannabinoids

    11.00-12.00 – Round table: discussion forum

    BREAK

    14.20-14.30 – Introducing Alessia Ligresti and Marialessandra Contino
    Chairs: Alessia Ligresti and Miriam Melis

    14.30 – Prof. Vincenzo Di Marzo (University of Laval)
    A biochemical and pharmacological perspective on the endocannabinoidome-gut microbiome axis

    15.00 – Prof. Ester Aso (University of Barcelona)
    A pharmacological perspective on the potential utility of natural cannabinoids against Alzheimer's disease

    15.30 – Prof. Dr. Franjo Grotenhermen (Canncura GmbH)
    A medical perspective on cannabinoids in skin diseases

    16-17.00 – Round table: discussion forum

    17th February 2025

    DAY 2

    TACKLING ONCOLOGY AND PAIN WITH CANNABINOIDS

    The Symposium will be held virtually from 9:30 – 17:00 CET

    9.20-9.30 - Welcoming (Alessia Ligresti and Marialessandra Contino)

    Alessia Ligresti and Manuel Guzman

    9.30 - Prof. Laura Heitman (Leiden University)
    A pharmacological perspective on cannabinoidrReceptor drug discovery - Adding kinetic context

    10.00 - Prof. Cristina Sanchez (Complutense University of Madrid)
    A biochemical perspective on the endocannabinoid system as a therapeutic tool in cancer progression

    10.30 - Dr. Colin Stott (Phytanix Bio)
    A regulatory perspective on the development of cannabis-based and cannabinoid medicines

    11.00-12.00 - Round table: discussion forum

    BREAK

    14.20-14.30 - Introducing Alessia Ligresti and Marialessandra Contino
    Marialessandra Contino and David Finn

    14.30 - Prof. Nadine Jagerovic (Spanish National Research Council)
    An academic medicinal chemistry perspective on the endocannabinoid system modulators

    15.00 - Prof. Katarzyna Starowicz (Maj Institute of Pharmacology, PAS)
    (Endo)cannabinoids as therapeutic option in chronic pain treatment

    15.30 - Prof. Jose Martinez-Orgado (Hospital Clínico "San Carlos”)
    A preclinical and clinical perspective on cannabinoids for newborn brain damage

    16-17.00 - Round table: discussion forum

    24th February 2025

    DAY 3

    TRANSLATE CANNABINOID SCIENCE INTO PRACTICE (industry-oriented session)

    The Symposium will be held virtually from 9:30 – 17:00 CET

    9.20-9.30 - Welcoming (Alessia Ligresti and Marialessandra Contino)

    Alessia Ligresti and Raquel Peyraube

    9.30 - Prof. Saoirse O’Sullivan (Artelo Biosciences)
    Driving FABP inhibition to the clinic

    10.00 - Prof. Andrea Chicca (Synendos Therapeutics)
    A translational perspective on first-in-class selective endocannabinoid reuptake inhibitors: from basic research to clinical development

    10.30 - Prof. Geoffrey Guy / Prof. Alistair Nunn (The Guy Foundation - GW Pharmaceuticals)
    The possible non-pharmacological basis of cannabinoid effects on biological systems

    11.00-12.00 - Round table: discussion forum

    BREAK

    14.20-14.30 - Introducing Alessia Ligresti and Marialessandra Contino
    Marialessandra Contino and Maria Majellaro

    14.30 - Dr. Uwe Grether (Roche)
    A medicinal chemistry perspective on Cannabinoid Receptor Type 2 - Snapshots from a drug discovery program

    15.00 - Dr. Hunter Land (Lupvindol Biosciences)
    A Polypharmacological Perspective on Cannabinoid Based Therapies

    15.30 - Prof. Dr. Kirsten R. Müller-Vahl (Hannover Medical School)
    A clinical perspective on cannabinoids in psychiatry

    16-17.00 - Round table: discussion forum